Family Nurse Practitioner Exam

Which statement about the Td vaccine is incorrect?

1. Fever occurs in up to 80% of patients

2. Side effects can include injection site induration

3. The Td vaccine is given every 10 years

4. The DPT and DT should not be given beyond the seventh birthday

The correct answer is: Fever occurs in up to 80% of patients

The Td vaccine, which protects against tetanus and diphtheria, typically has a low occurrence of fever as a side effect. While some patients may experience mild side effects such as soreness at the injection site or low-grade fever, the statement that fever occurs in up to 80% of patients is exaggerated and unsupported by clinical data. Most reports suggest that systemic reactions, including fever, are rare. The other statements reflect accurate information regarding the Td vaccine. Injection site induration is a known side effect, indicating that some patients may experience localized swelling or firmness at the site of administration. It is also correct that the Td vaccine is recommended every 10 years to maintain immunity against tetanus and diphtheria. Additionally, the DPT (Diphtheria, Pertussis, Tetanus) and DT (Diphtheria, Tetanus) vaccines are generally not administered beyond the seventh birthday, as the formulations and recommendations change after this age due to safety and efficacy considerations. Thus, the identification of fever as a common side effect at such a high rate clearly distinguishes the first statement as incorrect.