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Fitz-Hugh-Curtis syndrome is most commonly associated with which infection?

  1. Syphilis

  2. Chlamydia trachomatis

  3. Herpes genitalis

  4. Lymphogranuloma venereum

The correct answer is: Chlamydia trachomatis

Fitz-Hugh-Curtis syndrome is a complication that arises as a result of a pelvic inflammatory disease (PID), which is frequently associated with infections caused by Chlamydia trachomatis. This condition involves inflammation of the liver capsule due to the dissemination of infection from the female reproductive organs. Chlamydia trachomatis is a common sexually transmitted infection that can lead to PID when it ascends to the upper reproductive tract, facilitating the pathophysiological changes that result in Fitz-Hugh-Curtis syndrome. This syndrome is characterized by right upper quadrant pain and may present with "violin string" adhesions on the liver surface seen during laparoscopy. While other infections listed may also be linked to PID, Chlamydia trachomatis is specifically noted as the most frequent cause of this syndrome due to its prevalence and association with inflammatory pelvic conditions. Therefore, its strong correlation with Fitz-Hugh-Curtis syndrome makes it the correct answer in this context.